TB-500 5mg

$60.00
10 in stock
10 in stock

For research use only. Not for human consumption.

TB-500 (Thymosin Beta-4 Fragment) is a synthetic 17-amino acid peptide that corresponds to a specific region of the naturally occurring thymosin beta-4 protein. It is primarily studied for its role in actin sequestration and regulation of cell migration and differentiation.

This high-purity research-grade peptide is intended for in vitro and in vivo laboratory studies investigating tissue repair, wound healing, and regenerative mechanisms.

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  • Research Grade - 99% Purity
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SKU: 23463

Description

This product is for research and laboratory use only. Not for human consumption, therapeutic, diagnostic, or veterinary purposes.

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4, a protein involved in actin regulation. The most commonly researched sequence is the heptadecapeptide (17 amino acids) LKKTETQ, which retains significant biological activity related to actin binding in laboratory models.

In scientific research, TB-500 is widely used to study:

  • Cell migration and differentiation
  • Wound healing and tissue regeneration processes
  • Actin cytoskeleton dynamics
  • Muscle, tendon, and ligament repair mechanisms
  • Anti-inflammatory pathways in animal and cell culture models

The peptide is supplied as a lyophilized white to off-white powder. Each batch is tested for high purity using HPLC and mass spectrometry to ensure consistency for reproducible research results.

Key Specifications:

  • Compound Name: TB-500 (Thymosin Beta-4 Fragment)
  • CAS Number: 77591-33-4
  • Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S (for the 17-amino acid fragment)
  • Molecular Weight: ~2,000 – 2,100 g/mol (average)
  • Peptide Length: 17 amino acids
  • Appearance: White to off-white lyophilized powder
  • Purity: ≥98% (HPLC), typical batches ≥99%
  • Solubility: Highly soluble in water and saline
  • Storage: Lyophilized: -20°C. Reconstituted: 2–8°C (short term)
  • Source: Synthetic (solid-phase peptide synthesis)
  • Testing: HPLC, Mass Spectrometry (identity & purity confirmation)

Research Applications TB-500 is a valuable research tool for studying tissue regeneration, wound healing, and cell motility. It is commonly used in laboratory models to investigate angiogenesis, collagen deposition, muscle recovery, and tendon/ligament repair mechanisms. Researchers often study it alongside other regenerative peptides such as BPC-157.

Storage & Handling Lyophilized Powder (Recommended long-term storage): Store at -20°C in a laboratory freezer in its original sealed vial. Properly stored, TB-500 powder remains stable for 12–24 months or longer. Short-term storage at 2–8°C (refrigerator) is acceptable for up to 3–6 months. Protect from moisture and light.

Reconstituted Solution: Reconstitute only the amount required for immediate experiments using sterile bacteriostatic water or appropriate laboratory buffer. Store reconstituted TB-500 at 2–8°C and use within 30 days for best results. For longer-term storage, divide into single-use aliquots and freeze at -20°C. Avoid repeated freeze-thaw cycles to maintain peptide integrity.

Quality Assurance

  • High-purity research-grade material
  • Batch-specific CoA with HPLC and MS data provided

Legal & Compliance This product is sold strictly for research and scientific investigation purposes only. It is not a pharmaceutical product and has not been approved by the Therapeutic Goods Administration (TGA) or any other regulatory authority. The buyer assumes full responsibility for ensuring compliance with all applicable Australian laws and regulations.

Additional information

Research Focus

Anti-Inflammatory Research, Muscle Recovery, Tendon & Ligament Research, Tissue Repair, Wound Healing